Update in COVID-19 in the intensive care unit from the 2020 HELLENIC Athens International symposium

Jordi Rello; Mirko Belliato; Meletios-Athanasios Dimopoulos; Evangelos J Giamarellos-Bourboulis; Vladimir Jaksic; Ignacio Martin-Loeches; Iosif Mporas; Paolo Pelosi; Garyphallia Poulakou; Spyridon Pournaras; Maximiliano Tamae-Kakazu; Jean-François Timsit; Grant Waterer; Sofia Tejada; George Dimopoulos

doi:10.1016/j.accpm.2020.10.008

Update in COVID-19 in the intensive care unit from the 2020 HELLENIC Athens International symposium

Anaesth Crit Care Pain Med. 2020 Dec;39(6):723-730. doi: 10.1016/j.accpm.2020.10.008. Epub 2020 Oct 22.

Authors

Jordi Rello¹, Mirko Belliato², Meletios-Athanasios Dimopoulos³, Evangelos J Giamarellos-Bourboulis⁴, Vladimir Jaksic⁵, Ignacio Martin-Loeches⁶, Iosif Mporas⁷, Paolo Pelosi⁸, Garyphallia Poulakou⁹, Spyridon Pournaras¹⁰, Maximiliano Tamae-Kakazu¹¹, Jean-François Timsit¹², Grant Waterer¹³, Sofia Tejada¹⁴, George Dimopoulos¹⁵

Affiliations

¹ Clinical Research/Epidemiology in Pneumonia & Sepsis (CRIPS), Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Clinical Research in the ICU, Anaesthesia Department, CHU Nimes, Université de Nimes-Montpellier, France.
² Anestesia e Rianimazione II Cardiopolmonare, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
³ Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
⁴ 4(th) Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Greece.
⁵ 3M Health Care, 3M Company, St. Paul, MN, USA.
⁶ Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Multidisciplinary Intensive Care Research Organization (MICRO), Department of Intensive Care Medicine, St. James's University Hospital, Dublin, Ireland; Trinity Centre for Health Sciences, Dublin, Ireland; Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, Spain.
⁷ School of Physics Engineering and Computer Science, University of Hertfordshire, Hatfield, United Kingdom.
⁸ Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; Anaesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy.
⁹ 3(rd) Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Sotiria General Hospital of Athens, Greece.
¹⁰ Laboratory of Clinical Microbioloy, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
¹¹ Division of Pulmonary, Critical Care and Sleep Medicine, Spectrum Health - Michigan State University, Grand Rapids, Michigan, USA.
¹² AP-HP, Bichat Hospital, Medical and Infectious Diseases ICU (MI2), F-75018 Paris, France; University of Paris, IAME, INSERM, F-75018 Paris, France.
¹³ School of Medicine, University of Western Australia, Australia.
¹⁴ Clinical Research/Epidemiology in Pneumonia & Sepsis (CRIPS), Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: stmagraner@gmail.com.
¹⁵ Department of Critical Care Medicine, National and Kapodistrian University of Athens, Medical School, Greece.

Abstract

The 2020 International Web Scientific Event in COVID-19 pandemic in critically ill patients aimed at updating the information and knowledge on the COVID-19 pandemic in the intensive care unit. Experts reviewed the latest literature relating to the COVID-19 pandemic in critically ill patients, such as epidemiology, pathophysiology, phenotypes of infection, COVID-19 as a systematic infection, molecular diagnosis, mechanical ventilation, thromboprophylaxis, COVID-19 associated co-infections, immunotherapy, plasma treatment, catheter-related bloodstream infections, artificial intelligence for COVID-19, and vaccination. Antiviral therapy and co-infections are out of the scope of this review. In this review, each of these issues is discussed with key messages regarding management and further research being presented after a brief review of available evidence.

Keywords: ARDS; Acute respiratory failure; COVID-19; Intensive care; Pneumonia; SARS-CoV-2.

Publication types

Review

MeSH terms

COVID-19 Nucleic Acid Testing / methods
COVID-19 Serotherapy
COVID-19 Vaccines
COVID-19* / diagnosis
COVID-19* / epidemiology
COVID-19* / physiopathology
COVID-19* / therapy
Congresses as Topic*
Global Health / statistics & numerical data
Humans
Immunization, Passive / methods
Immunotherapy / methods
Intensive Care Units*
Pandemics
Phenotype
SARS-CoV-2*
Symptom Assessment
Thromboembolism / prevention & control
Videoconferencing
Virus Internalization

Substances

COVID-19 Vaccines