Gut Health = Mental Health? The Impact of Diet and Dietary Supplements on Mood Disorders

Curr Nutr Rep. 2020 Dec;9(4):361-368. doi: 10.1007/s13668-020-00340-2. Epub 2020 Nov 10.

Abstract

Purpose of review: Depression and mood disorders impact a significant number of our population. The purpose of this review was to investigate the current literature on dietary strategies or supplements that may impact mood and cognition.

Recent findings: Several recent studies and reviews have found that promoting a "healthy" diet may help improve depressive symptoms, and that such interventions are cost-effective. Other reviews have found that there may be some benefit to multiple dietary interventions/supplementations on a variety of mood disorders. While these studies offer a safe, cost-effective option, the quality of evidence is poor. Regardless, promoting a healthy diet including healthy fats, whole grains, and a variety of fruits and vegetables promotes not only mental health, but also a variety of other chronic conditions. Thus, while not ready as standalone therapy, dietary counseling/intervention should be included as we address mental health concerns of our patients.

Keywords: Depression; Ketogenic diet; Mediterranean diet; Mood disorders; Probiotics.

Publication types

  • Review

MeSH terms

  • Acetylcysteine
  • Chronic Disease
  • Diet*
  • Diet, Healthy
  • Dietary Supplements*
  • Fatty Acids, Omega-3
  • Fruit
  • Gastrointestinal Tract*
  • Humans
  • Isoflavones
  • Mental Health*
  • Micronutrients
  • Mood Disorders*
  • Probiotics
  • Proteins
  • Quercetin
  • Vegetables
  • Vitamin D

Substances

  • Fatty Acids, Omega-3
  • Isoflavones
  • Micronutrients
  • Proteins
  • Vitamin D
  • Quercetin
  • Acetylcysteine