Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

Go Un Roh; Joon Gwon Kang; Jung Youn Han; Chul Ho Chang

doi:10.1186/s12871-020-01201-9

Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

BMC Anesthesiol. 2020 Nov 10;20(1):282. doi: 10.1186/s12871-020-01201-9.

Authors

Go Un Roh¹, Joon Gwon Kang¹, Jung Youn Han¹, Chul Ho Chang²

Affiliations

¹ Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-ro, Bundang-gu, Seongnami-si, Gyeonggi-do, 13496, Korea.
² Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Gangnam Severance Hospital, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea. anezzang@yuhs.ac.

Abstract

Background: Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOB intubation) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOB intubation could minimize the risk of desaturation and improve the visual field. Therefore, the aim of this prospective randomized controlled study was to evaluate the utility and safety of oxygen insufflation through the working channel during FOB intubation in apneic patients.

Methods: Thirty-six patients were randomly allocated to an N group (no oxygen insufflation) or an O group (oxygen insufflation). After preoxygenation, FOB intubation was performed with (O group) or without (N group) oxygen insufflation in apneic patients. The primary outcome was the velocity of decrease in the partial pressure of oxygen (PaO₂) during FOB intubation (V_PaO2, mmHg/sec) defined as the difference of PaO₂ before and after intubation divided by the time to intubation. The secondary outcomes included the success rate for FOB intubation, time to intubation, visual field during FOB intubation, findings of arterial blood gas analysis, and occurrence of FOB intubation-related complications.

Results: We found that V_PaO2 was significantly greater in the N group than in the O group (1.0 ± 0.4 vs. 0.4 ± 0.4; p < 0.001), while the visual field was similar between groups. There were no significant intergroup differences in the secondary outcomes.

Conclusions: These findings suggest that oxygen insufflation through the working channel during FOB intubation aids in extending the apneic window during the procedure.

Trial registration: ClinicalTrials.gov , NCT02625194 , registered at December 9, 2015.

Keywords: Apneic oxygenation; Fiberoptic intubation; Oxygenation during intubation.

Publication types

Randomized Controlled Trial

MeSH terms

Apnea / physiopathology*
Female
Fiber Optic Technology*
Humans
Insufflation / methods*
Intubation, Intratracheal / methods*
Male
Middle Aged
Oxygen / administration & dosage*
Prospective Studies

Substances

Oxygen

Associated data

ClinicalTrials.gov/NCT02625194