Spasmodic Dysphonia

Adv Otorhinolaryngol. 2020:85:133-143. doi: 10.1159/000456693. Epub 2020 Nov 9.

Abstract

Spasmodic dysphonia (SD) is a rare focal laryngeal dystonia. It is characterized by task-specific voice dysfluency resulting from selective intrinsic laryngeal musculature hyperfunction. Symptoms may be attenuated by a sensory trick. Although SD can be seen at times in generalized dystonia syndromes, it is typically a sporadic phenomenon. Involvement of the laryngeal adductor muscles is more common than abductor muscles. The standard treatment of this disorder is with botulinum toxin injection, usually electromyography-guided, which must be repeated periodically as the toxin wears off. A number of non-reversible surgical procedures have also been described to mitigate the symptoms. Other treatment modalities are under investigation, including implantable electrical stimulation devices and deep brain stimulation.

Publication types

  • Review

MeSH terms

  • Botulinum Toxins, Type A / therapeutic use
  • Dysphonia / diagnosis
  • Dysphonia / etiology
  • Dysphonia / therapy*
  • Electric Stimulation Therapy
  • Electromyography
  • Humans
  • Laryngeal Muscles*
  • Neuromuscular Agents / therapeutic use
  • Spasm / diagnosis
  • Spasm / etiology
  • Spasm / therapy*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A