A Rare Case with Systemic Lupus Erythematosus Manifested by two Different Neurologic Entities; Guillain Barre Syndrome and Posterior Reversible Encephalopathy Syndrome

Firdevs Ulutaş; Veli Çobankara; Uğur Karasu; Nuri Baser; Ismail Hakkı Akbudak

doi:10.31138/mjr.31.3.358

A Rare Case with Systemic Lupus Erythematosus Manifested by two Different Neurologic Entities; Guillain Barre Syndrome and Posterior Reversible Encephalopathy Syndrome

Mediterr J Rheumatol. 2020 Sep 30;31(3):358-361. doi: 10.31138/mjr.31.3.358. eCollection 2020 Sep.

Authors

Firdevs Ulutaş¹, Veli Çobankara¹, Uğur Karasu¹, Nuri Baser², Ismail Hakkı Akbudak³

Affiliations

¹ Department of Rheumatology.
² Department of Internal Medicine.
³ Department of Intensive Care Unit, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

Abstract

Systemic lupus erythematosus (SLE) is an immune-mediated, lifelong disease characterized by quite heterogeneous neuropsychiatric manifestations. Herewith, we report the first rare co-incidental case with posterior reversible encephalopathy syndrome (PRES), Guillain Barre Syndrome (GBS), and (SLE). The coexistence of these neurological conditions in SLE patients could lead to delayed diagnosis and treatment due to this rare coalescence and clinical diversity. Currently, there are no specific, diagnostic radiological or laboratory biomarkers for neurological involvement in SLE. Awareness and, early recognition of neuropsychiatric involvements of the disease are important for timely appropriate treatment. Delayed treatment may cause permanent damage, poor prognosis, long term morbidity, and even death.

Keywords: Guillain-Barre Syndrome; Systemic lupus erythematosus; posterior reversible encephalopathy syndrome.

Publication types

Case Reports