Triglyceride Deposit Cardiomyovasculopathy with Massive Myocardial Triglyceride which Was Proven Using Proton-magnetic Resonance Spectroscopy

Intern Med. 2021 Apr 15;60(8):1217-1220. doi: 10.2169/internalmedicine.6126-20. Epub 2020 Nov 9.

Abstract

The patient was a 73-year-old man with a history of hypertension, diabetes mellitus, dyslipidemia, rheumatoid arthritis, repeated percutaneous coronary intervention and percutaneous peripheral intervention procedures. He was frequently admitted to our hospital for congestive heart failure with orthopnea. The myocardial washout rate of iodine-123-β-methyl iodophenyl-pentadecanoic acid was defective on scintigraphy. He was diagnosed with triglyceride deposit cardiomyovasculopathy (TGCV). Proton magnetic resonance spectroscopy (1H-MRS) indicated the level of myocardial triglyceride (TG) content to be extremely high (4.92%). This is the first report to confirm a massive accumulation of TG in the myocardium of a patient with TGCV using 1H-MRS noninvasively.

Keywords: proton magnetic resonance spectroscopy; triglyceride deposit cardiomyovasculopathy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Lipase*
  • Male
  • Myocardium
  • Proton Magnetic Resonance Spectroscopy
  • Protons*
  • Triglycerides

Substances

  • Protons
  • Triglycerides
  • Lipase