Factors Associated with Delay of Emergency Medical Services Activation in Patients with Acute Stroke

J Stroke Cerebrovasc Dis. 2021 Jan;30(1):105426. doi: 10.1016/j.jstrokecerebrovasdis.2020.105426. Epub 2020 Nov 9.

Abstract

Background: The poor prognosis of acute stroke may be largely attributed to delays in treatment. Emergency medical services (EMS) usage is associated with a significant reduction in the delay in stroke treatment. The aims of this study were to identify factors associated with the delay in EMS activation for patients with acute stroke.

Methods: This study was conducted at 26 Fire Safety Centers in five districts of Seoul, Korea. Patients with acute stroke transferred by EMS and admitted to a tertiary referral hospital from January 2014 to December 2018 were enrolled. In this cross-sectional study, the dependent variable was the time from stroke onset to EMS activation time. Patients were divided into two groups, onset-to-alarm time ≤ 30 min and onset-to-alarm time > 30 min, and previously collected patient data were analyzed. We performed logistical regression analyses of characteristics differing significantly between groups.

Results: Out of 480 patients, 197 (41%) had onset-to-alarm times > 30 min. Significant variables in the logistical analysis were alert mental state (adjusted odds ratio [aOR]: 2.77; 95% confidence interval [CI]: 1.31-6.13), pre-stroke mRS ≥ 2 (aOR: 2.46; 95% CI: 1.26-4.95), onset occurrence at private space (aOR: 2.31; 95% CI: 1.23-4.41), recognizing symptoms between 0 and 8 am (aOR: 2.30; 95% CI: 1.25-4.31), ischemic stroke (aOR: 1.88; 95% CI: 1.04-3.43), and witnessed by others (aOR: 0.32; 95% CI: 0.18-0.55).

Conclusions: Delay in EMS activation for acute stroke cases is possibly related to difficult situations to recognize stroke symptoms, such as alert mental state, pre-stroke mRS ≥ 2, onset occurrence at private space, recognizing symptoms between 0 and 8 am, and unwitnessed by others.

Keywords: Emergency medical dispatch; Emergency medical services; Stroke; Time-to-treatment.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Emergency Medical Services*
  • Female
  • Health Services Accessibility*
  • Humans
  • Ischemic Stroke / complications
  • Ischemic Stroke / diagnosis
  • Ischemic Stroke / therapy*
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Seoul
  • Symptom Assessment
  • Time Factors
  • Time-to-Treatment*