New and Emerging Technologies in Type 1 Diabetes

Endocrinol Metab Clin North Am. 2020 Dec;49(4):667-678. doi: 10.1016/j.ecl.2020.07.006. Epub 2020 Oct 14.

Abstract

There has been a rapid advancement in the pace of development of new diabetes technologies and therapies for the management of type 1 diabetes over the past decade. The Diabetes Control and Complications Trial conclusively established that tight glycemic control with intensive insulin therapy decreases the rates of diabetes complications in proportion to glycemic control, and diabetes technologies have accordingly been developed to help patients reach these goals. In this review, the authors discuss new diabetes therapeutics and technologies, including new insulin analogues, insulin pumps, continuous glucose monitoring systems, and automated insulin delivery systems."

Keywords: Artificial pancreas (AP); Automated insulin delivery (AID); Bionic pancreas; Closed-loop; Continuous glucose monitoring (CGM); Glucagon; Insulin; Ultrarapid-acting insulin.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Glucose*
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / therapy*
  • Gastrointestinal Agents / administration & dosage*
  • Humans
  • Hypoglycemic Agents / administration & dosage*
  • Insulin / administration & dosage*
  • Insulin Infusion Systems*
  • Monitoring, Ambulatory*
  • Pancreas, Artificial*
  • Telemedicine*

Substances

  • Blood Glucose
  • Gastrointestinal Agents
  • Hypoglycemic Agents
  • Insulin