[Ebola, the first vaccines available]

Med Sci (Paris). 2020 Nov;36(11):1027-1033. doi: 10.1051/medsci/2020174. Epub 2020 Nov 5.
[Article in French]

Abstract

In the recent years, Ebola virus has been responsible for several major epidemics. Research efforts have allowed the development and evaluation in the field of several vaccine candidates. At present, two of them are already approved and used in the fight against the virus in the Democratic Republic of Congo. This review aims to describe the different candidates, the clinical trials that have been conducted as well as the first results in the field.

Title: Ebola, des premiers vaccins disponibles.

Abstract: Ces dernières années, le virus Ebola a été responsable d’épidémies de grande ampleur. Les efforts de recherche ont permis la mise au point et l’évaluation sur le terrain de plusieurs candidats vaccins. À l’heure actuelle, deux sont déjà homologués et utilisés dans la lutte contre le virus en République démocratique du Congo. Cette revue se propose de faire le point sur les différents candidats vaccins, les essais cliniques qui ont été menés et les premiers résultats de terrain.

Publication types

  • Review

MeSH terms

  • Disease Outbreaks
  • Ebola Vaccines / therapeutic use*
  • Ebolavirus / immunology*
  • Epidemics
  • Health Services Needs and Demand
  • Hemorrhagic Fever, Ebola / epidemiology
  • Hemorrhagic Fever, Ebola / immunology
  • Hemorrhagic Fever, Ebola / therapy*
  • Humans
  • Mass Vaccination / organization & administration
  • Mass Vaccination / statistics & numerical data
  • Socioeconomic Factors

Substances

  • Ebola Vaccines

Grants and funding