Skin scars and wrinkles temporary camouflage in dermatology and oncoesthetics: focus on acetyl hexapeptide-8

Clin Ter. 2020 Nov-Dec;171(6):e539-e548. doi: 10.7417/CT.2020.2270.

Abstract

Objective: The aim of study is to evaluate the aesthetic outcome of specific formulated cosmeceutical product to mask and reduce the appearance surgical scars or unappealing skin tags in chronic diseases, such as cancer

Methods: In a spontaneous, anecdotal, retrospective study, 26 patients with skin disorders appealed to Second Opinion Medical Network (Modena, Italy), required masking and improving the skin appearance. To evaluate the aesthetic improvement of skin imperfections, a gelcream containing 10% of acetyl hexapeptide-8 (registered trademark Argireline®) was selected, that can be applied directly upon the lesion, followed by a light massage in the treated area for a few minutes

Results: The skin quality parameters (hydration, elasticity, sebum), photographs and investigators clinical assessment have been performed before and after the treatment and demonstrated that this cream significantly improved the skin values and the self-image expectation of each patient. No allergic reactions were documented during the period treatment

Conclusions: The topical administration of this cosmeceutical cream is a safe and effective alternative to the invasive procedures, to improve the quality of life in patients with some skin disorders such as cancer, surgical scars, hidradenitis, aging wrinkles

Keywords: Acetyl hexapeptide-8; Cosmeceutical cream; Oncological treatment; Quality of life; Scars; Topical treatment.

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Cicatrix / drug therapy*
  • Cicatrix / pathology
  • Dermatology
  • Female
  • Humans
  • Italy
  • Middle Aged
  • Oligopeptides / pharmacology*
  • Quality of Life
  • Retrospective Studies
  • Skin / drug effects*
  • Skin / pathology
  • Skin Aging / drug effects*
  • Treatment Outcome
  • Young Adult

Substances

  • Oligopeptides
  • acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide