Platinum(II) complex with 4-nitro-N-(pyridin-2-ylmethylidene)aniline: synthesis, characterization, crystal structure and antioxidant activity

Abstract

A novel complex has been prepared using the (E)-4-nitro-N-(pyridin-2-ylmethylidene)aniline bidentate Schiff base ligand and PtCl₂, namely, dichlorido[(E)-4-nitro-N-(pyridin-2-ylmethylidene)aniline-κ²N,N']platinum(II) acetonitrile hemisolvate, [PtCl₂(C₁₂H₉N₃O₂)]·0.5CH₃CN, 1. According to the X-ray measurements of the crystal structure, the Pt^II ion adopts a PtCl₂N₂ square-planar coordination. The coordination of the Schiff base ligand to the Pt^II ion occurs in a cyclic bidentate fashion, as a result of which a five-membered metallacycle is formed. Furthermore, in the structure of 1, the neutral molecules form a one-dimensional chain structure through C-H...Cl and C-H...O hydrogen bonds. The characterization of the complex was performed via single-crystal X-ray diffraction, IR spectroscopy and elemental analysis, and the antioxidant activity of the complex was evaluated using spectrophotometry by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method.

Keywords: ABTS; DPPH; amine; antioxidant activity; bidentate Schiff base; crystal structure; inhibition; platinum.