Complete Resection of Phosphoglyceride Crystal Deposition Disease After Cardiac Surgery

Ann Thorac Surg. 2021 May;111(5):e315-e317. doi: 10.1016/j.athoracsur.2020.07.099. Epub 2020 Nov 2.

Abstract

Phosphoglycerides are the major lipid component of all cell membranes. Phosphoglyceride crystal deposition disease (PCDD) is defined as the deposition of phosphoglyceride crystals and is considered a lipid metabolic disorder. It predominantly involves injured soft tissues, ultimately forming foreign body granulomas. We present a case of complete resection of PCDD in a 48-year-old woman, in whom the PCDD originated from a myocardial wound created at the time of surgical repair of a ventricular septal defect 40 years ago. We underscore that familiarity with this disease entity will help to stimulate accurate diagnosis and timely treatment.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Surgical Procedures / adverse effects*
  • Female
  • Glycerophospholipids / metabolism*
  • Granuloma, Foreign-Body / etiology
  • Granuloma, Foreign-Body / metabolism
  • Granuloma, Foreign-Body / surgery*
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / metabolism
  • Heart Ventricles / surgery*
  • Humans
  • Middle Aged
  • Myocardium / metabolism*
  • Myocardium / pathology
  • Postoperative Complications*
  • Reoperation

Substances

  • Glycerophospholipids