Fabrication and properties of carboxymethyl chitosan/polyethylene oxide composite nonwoven mats by centrifugal spinning

Chen Li; Yu Huang; Renhao Li; Yun Wang; Xin Xiang; Chunhua Zhang; Dong Wang; Yingshan Zhou; Xin Liu; Weilin Xu

doi:10.1016/j.carbpol.2020.117037

Fabrication and properties of carboxymethyl chitosan/polyethylene oxide composite nonwoven mats by centrifugal spinning

Carbohydr Polym. 2021 Jan 1:251:117037. doi: 10.1016/j.carbpol.2020.117037. Epub 2020 Sep 4.

Authors

Chen Li¹, Yu Huang², Renhao Li³, Yun Wang¹, Xin Xiang¹, Chunhua Zhang⁴, Dong Wang⁵, Yingshan Zhou⁶, Xin Liu⁷, Weilin Xu¹

Affiliations

¹ State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China.
² College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China; Hubei Key Laboratory of Advanced Textile Materials & Application, Wuhan Textile University, Wuhan 430200, China.
³ College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China.
⁴ State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China; College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China.
⁵ Hubei Key Laboratory of Advanced Textile Materials & Application, Wuhan Textile University, Wuhan 430200, China.
⁶ State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China; College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China. Electronic address: zyssyz@126.com.
⁷ State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China; College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China. Electronic address: xinliu_wtu@163.com.

PMID: 33142595
DOI: 10.1016/j.carbpol.2020.117037

Abstract

Carboxymethyl chitosan/polyethylene oxide (CMCS/PEO) mixed composition nonwoven mats with the average mat basis weight of 34.53-49.63 g/m² were prepared by centrifugal spinning from homogeneous aqueous solution for potential use as wound dressings. The weight fraction composition of CMCS/PEO investigated was 40/60 to 60/40. The CMCS/PEO fibers were found to have normally distributed, monomodal, average diameters ranging from 1.91 μm (55 % CMCS) to 3.22 μm (50 % CMCS). Addition of CMCS to PEO (40 % CMCS) resulted in appearance of a wide angle x-ray diffraction (WXRD) peak at 18.9°. The CMCS and PEO fibers were demonstrated by differential scanning calorimetry and WXRD to be mixtures of the two paracrystalline polymers. The composite nonwoven mats with 60 % weight of CMCS demonstrated Log2 reduction at 24 h against Staphylococcus aureus inoculation (104 cfg/mL).

Keywords: Carboxymethyl chitosan; Centrifugal spinning; Nonwoven; Polyethylene oxide; Wound dressing.