Coronavirus disease 2019: scientific overview of the global pandemic

A Dey; R Das; H S Misra; S Uppal

doi:10.1016/j.nmni.2020.100800

Coronavirus disease 2019: scientific overview of the global pandemic

New Microbes New Infect. 2020 Nov:38:100800. doi: 10.1016/j.nmni.2020.100800. Epub 2020 Oct 28.

Authors

A Dey¹, R Das^{1

2}, H S Misra^{1

2}, S Uppal^{1

2}

Affiliations

¹ Molecular Genetics Section, Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
² Homi Bhabha National Institute, Anushakti Nagar, Mumbai, India.

Abstract

Coronavirus disease 2019 (COVID-19) is the disease caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genome sequencing of the virus revealed that it is a new zoonotic virus that might have evolved by jumping from bats to humans with one or more intermediate hosts. The immediate availability of the sequence information in the public domain has accelerated the development of quantitative RT-PCR-based diagnostics. Numerous clinical trials have been prioritized globally for testing new vaccines and treatments against this disease. This review provides a broad insight into different aspects of COVID-19, an introduction to SARS-CoV-2 mitigation strategies and the present status of diagnostics and therapeutics.

Keywords: COVID-19; Cov-2; SARS; coronavirus; diagnostics; disease; global; pandemic; ssRNA; virus.

Publication types

Review