Familial adenomatous polyposis: a case study

Joseph Yorke; Francis Akwaw Yamoah; Ronald Awoonor-Williams; Thomas Okpoti Konney; Emmanuel Acheampong; Ernest Adjei; Kwabena Acheamfour Ababio; Daniel Gyawu Aning; Dennis Afful-Yorke; Freda Manu Aidoo; Claudia Gyamfua Assim; Frank Enoch Gyamfi; Raphael Owusu Sekyere Assim; Saabea Owusu Konadu; David Elikplim Kuwornu; Emmanuella Nsenbah Acheampong

doi:10.1093/jscr/rjaa367

Familial adenomatous polyposis: a case study

J Surg Case Rep. 2020 Oct 27;2020(10):rjaa367. doi: 10.1093/jscr/rjaa367. eCollection 2020 Oct.

Authors

Joseph Yorke¹, Francis Akwaw Yamoah¹, Ronald Awoonor-Williams¹, Thomas Okpoti Konney², Emmanuel Acheampong³, Ernest Adjei⁴, Kwabena Acheamfour Ababio⁵, Daniel Gyawu Aning¹, Dennis Afful-Yorke¹, Freda Manu Aidoo⁶, Claudia Gyamfua Assim⁷, Frank Enoch Gyamfi⁸, Raphael Owusu Sekyere Assim⁶, Saabea Owusu Konadu¹, David Elikplim Kuwornu¹, Emmanuella Nsenbah Acheampong³

Affiliations

¹ General Surgery Unit, Directorate of Surgery, Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.
² Directorate of Obstetrics and Gynaecology, Kumasi, Ghana.
³ Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
⁴ Directorate of Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
⁵ Directorate of Anaesthesia and Intensive Care, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
⁶ Directorate of Accident and Emergency, Komfo Anokye Teaching Hospital, KATH, Kumasi, Ghana.
⁷ Directorate of Accident and Emergency, Cape Coast Teaching Hospital, Cape Coast, Ghana.
⁸ Department of Surgery, School of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Abstract

Familial adenomatous polyposis (FAP) is an inherited syndrome characterized by several adenomatous polyps of the gastrointestinal (GI) mucosa. If treatment is not provided, an average individual with classic FAP will develop colorectal carcinoma around the age of 40 years. The incidence rate of FAP in developing countries like Ghana is unknown compared to advanced countries. We present the first FAP case of a 22-year-old Ghanaian female who presented with massive lower GI bleeding and underwent surgical management after a thorough investigation. The initial assumption that colonic polyps are scarce in native Africans may be more than what is perceived. This highlights the need for the availability of endoscopic services in Ghana.

Keywords: colonoscopy; familial adenomatous polyposis; subtotal colectomy.

Publication types

Case Reports