Research Progress of Hair Cell Protection Mechanism

Yurong Mu; Hongguo Su; Fan Wu; Jianming Yang; Dan Li

doi:10.1155/2020/8850447

Research Progress of Hair Cell Protection Mechanism

Neural Plast. 2020 Oct 9:2020:8850447. doi: 10.1155/2020/8850447. eCollection 2020.

Authors

Yurong Mu¹, Hongguo Su², Fan Wu³, Jianming Yang⁴, Dan Li¹

Affiliations

¹ Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
² Department of Otorhinolaryngology, Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
³ Otorhinolaryngology Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 West Yan Jiang Road, Guangzhou 510120, China.
⁴ Department of Otorhinolaryngology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.

Abstract

How to prevent and treat hearing-related diseases through the protection of hair cells (HCs) is the focus in the field of hearing in recent years. Hearing loss caused by dysfunction or loss of HCs is the main cause of hearing diseases. Therefore, clarifying the related mechanisms of HC development, apoptosis, protection, and regeneration is the main goal of current hearing research. This review introduces the latest research on mechanism of HC protection and regeneration.

Publication types

Review

MeSH terms

Animals
Apoptosis
Hair Cells, Auditory / physiology*
Hearing / physiology*
Hearing Loss / physiopathology
Humans