A randomized, vehicle-controlled clinical trial of a synthetic TRPM8 agonist (Cryosim-1) gel for itch

J Am Acad Dermatol. 2021 Mar;84(3):869-871. doi: 10.1016/j.jaad.2020.10.065. Epub 2020 Oct 28.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Afferent Pathways / drug effects
  • Antipruritics / administration & dosage*
  • Chronic Urticaria / complications
  • Chronic Urticaria / drug therapy
  • Eczema / complications
  • Eczema / drug therapy
  • Gels
  • Herpes Zoster / complications
  • Herpes Zoster / drug therapy
  • Humans
  • Nociception / drug effects
  • Prospective Studies
  • Pruritus / diagnosis
  • Pruritus / drug therapy*
  • Pruritus / etiology
  • Pruritus / pathology
  • Severity of Illness Index
  • Skin / drug effects
  • Skin / innervation
  • Skin / pathology
  • TRPM Cation Channels / agonists*
  • Treatment Outcome

Substances

  • Antipruritics
  • Gels
  • TRPM Cation Channels
  • TRPM8 protein, human