Unlocking the mechanisms behind the formation of interlocking pavement cells

Abstract

The leaf epidermal pavement cells with the puzzle-piece shape offer an attractive system for studying the mechanisms underpinning cell morphogenesis in a plant tissue. The formation of the interdigitated lobes and indentations in these interlocking cells relies on the integration of chemical and mechanical signals and cell-to-cell signals to establish interdigitated polar sites defining lobes and indentations. Recent computational and experimental studies have suggested new roles of cell walls, their interplay with mechanical signals, cell polarity signaling regulated by auxin and brassinosteriods, and the cytoskeleton in the regulation of pavement cell morphogenesis. This review summarizes the current state of knowledge on these regulatory mechanisms behind pavement cell morphogenesis in plants and discusses how they could be integrated spatiotemporally to generate the interdigitated polarity patterns and the interlocking shape in pavement cells.