Agnostic biomarkers in gastrointestinal tumors: microsatellite instability and NTRK

Per Med. 2021 Jan;18(1):5-7. doi: 10.2217/pme-2020-0036. Epub 2020 Oct 30.
No abstract available

Keywords: NTRK; agnostic; biomarker; checkpoint inhibitors; colon cancer; gastrointestinal; microsatellite instability; tumor.

Publication types

  • Editorial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Benzamides / therapeutic use
  • Biomarkers
  • Female
  • Gastrointestinal Neoplasms / drug therapy*
  • Humans
  • Immune Checkpoint Inhibitors / therapeutic use*
  • Indazoles / therapeutic use
  • Male
  • Microsatellite Instability*
  • Middle Aged
  • Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Pyrazoles / therapeutic use
  • Pyrimidines / therapeutic use

Substances

  • Benzamides
  • Biomarkers
  • Immune Checkpoint Inhibitors
  • Indazoles
  • Pyrazoles
  • Pyrimidines
  • Protein-Tyrosine Kinases
  • entrectinib
  • larotrectinib