Reappraisal of haemorrhagic suprasellar pilocytic astrocytoma during adulthood

BMJ Case Rep. 2020 Oct 29;13(10):e235662. doi: 10.1136/bcr-2020-235662.

Abstract

Pilocytic astrocytomas comprise the most common central nervous system tumour during childhood and have an excellent response to surgical treatment in this population. The tumour incidence decreases with age, whereas more aggressive behaviour tends to increase. Haemorrhage as a presenting feature of pilocytic astrocytomas is a rare phenomenon, especially in the adult population. We present a case of a 55-year-old patient with progressive headaches and dizziness. MRI confirmed a sellar and predominantly retrochiasmal suprasellar lesion with heterogeneous signal, enhancement and blood products. Management via transsphenoidal approach was performed, and histopathology revealed the unexpected diagnosis of haemorrhagic pilocytic astrocytoma. Haemorrhagic pilocytic astrocytoma is an infrequent entity in the adult population and it is essential to recognise the peculiarities regarding diagnostic evaluation and management, which differ from the paediatric population. During adulthood, this tumour carries an overall unfavourable prognosis, with higher rates of progression and recurrence.

Keywords: CNS cancer; neuroendocrinology; neuroimaging; neurooncology; neurosurgery.

Publication types

  • Case Reports

MeSH terms

  • Astrocytoma / complications
  • Astrocytoma / diagnosis*
  • Brain / diagnostic imaging*
  • Brain Neoplasms / complications
  • Brain Neoplasms / diagnosis*
  • Cerebral Ventricles / diagnostic imaging*
  • Humans
  • Intracranial Hemorrhages / diagnosis
  • Intracranial Hemorrhages / etiology*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Sella Turcica / diagnostic imaging*
  • Tomography, X-Ray Computed