Microsporidial stromal keratitis in an immunocompromised patient: Successful management with medical therapy

Amanjot Kaur; Srikant K Sahu; Sanchita Mitra; Sujata Das

doi:10.4103/ijo.IJO_2348_20

Microsporidial stromal keratitis in an immunocompromised patient: Successful management with medical therapy

Indian J Ophthalmol. 2020 Nov;68(11):2552-2554. doi: 10.4103/ijo.IJO_2348_20.

Authors

Amanjot Kaur¹, Srikant K Sahu¹, Sanchita Mitra¹, Sujata Das¹

Affiliation

¹ L V Prasad Eye Institute, Bhubaneswar, Odisha, India.

Abstract

Microsporidial stromal keratitis is refractory to topical drugs and is classically described in immunocompetent hosts. A 55-year-old patient with renal transplant and oral immunosuppressants, presented with a 15-day history of redness, pain, and diminution of vision in the right eye. Slit-lamp examination revealed epithelial defect and mid-stromal infiltrate. On corneal scraping, microsporidial spores were observed. The patient was started on topical 0.02% polyhexamethylene biguanide (PHMB) and the infiltrate resolved after 6 weeks of initiation of topical therapy.

Keywords: Medical therapy; microsporidia; polyhexamethylene biguanide; stromal keratitis.

Publication types

Case Reports

MeSH terms

Eye Infections, Fungal* / diagnosis
Eye Infections, Fungal* / drug therapy
Humans
Keratitis* / diagnosis
Keratitis* / drug therapy
Microsporidiosis* / diagnosis
Microsporidiosis* / drug therapy
Middle Aged
Slit Lamp Microscopy