SARS-CoV-2 infection in an infant with severe dilated cardiomyopathy

Cardiol Young. 2021 Mar;31(3):485-487. doi: 10.1017/S1047951120004060. Epub 2020 Oct 29.

Abstract

A four- and a half-month-old girl with severe dilated cardiomyopathy due to neonatal enterovirus myocarditis, treated with diuretics and milrinone for the past 4 months, was infected with SARS-CoV-2. The disease course was characterised by high fever and gastrointestinal symptoms. Cardiac function, as measured by echocardiography, remained stable. The treatment focused on maintaining a normal heart rate and a stable fluid balance. In children with severe underlying cardiac disease, even a mild SARS-CoV-2 infection can require close monitoring and compound treatment.

Keywords: COVID-19; SARS-CoV-2; dilated cardiomyopathy; heart failure; infant.

Publication types

  • Case Reports

MeSH terms

  • COVID-19 / complications
  • COVID-19 / physiopathology*
  • Cardiomyopathy, Dilated / drug therapy
  • Cardiomyopathy, Dilated / etiology
  • Cardiomyopathy, Dilated / metabolism
  • Cardiomyopathy, Dilated / physiopathology*
  • Cardiotonic Agents / therapeutic use
  • Diarrhea / physiopathology*
  • Diuretics / therapeutic use
  • Echocardiography
  • Enterovirus Infections / complications
  • Female
  • Fever / physiopathology*
  • Heart Rate
  • Heart Transplantation
  • Humans
  • Infant
  • Milrinone / therapeutic use
  • Myocarditis / complications
  • Natriuretic Peptide, Brain / metabolism
  • Peptide Fragments / metabolism
  • SARS-CoV-2
  • Severity of Illness Index
  • Tachycardia / physiopathology*
  • Tachypnea / physiopathology*
  • Troponin T / metabolism
  • Ventricular Dysfunction, Left / drug therapy
  • Ventricular Dysfunction, Left / etiology
  • Ventricular Dysfunction, Left / metabolism
  • Ventricular Dysfunction, Left / physiopathology*
  • Vomiting / physiopathology*
  • Waiting Lists
  • Water-Electrolyte Balance

Substances

  • Cardiotonic Agents
  • Diuretics
  • Peptide Fragments
  • Troponin T
  • pro-brain natriuretic peptide (1-76)
  • Natriuretic Peptide, Brain
  • Milrinone