Prospective, multi-centre trial of mortality following general or spinal anaesthesia for hip fracture surgery in the elderly

Br J Anaesth. 1987 Sep;59(9):1080-8. doi: 10.1093/bja/59.9.1080.

Abstract

In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% with general, anaesthesia. The difference was not significant (95% confidence limits: -3.5 to +4.8). At 1 year following surgery, the mortality was 20.4%. Increasing age, ischaemic heart disease, cardiac failure, preoperative arrhythmias and poor ASA status were all associated with increases in early and long term mortality. A delay to surgery of more than 24 h from admission was also associated with an increased 28-day mortality. Senile dementia and admission other than from the patient's own home, were factors associated with a poorer long term outcome. From the point of view of mortality, subarachnoid anaesthesia did not appear to confer any advantages over general anaesthesia in non-prosthetic surgery for hip fracture in the elderly.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anesthesia, General / mortality*
  • Anesthesia, Spinal / mortality*
  • Clinical Trials as Topic
  • Emergencies
  • Female
  • Hip Fractures / surgery*
  • Humans
  • Male
  • Postoperative Complications / mortality
  • Prospective Studies
  • Random Allocation