The study of nanofluids is the most debated subject for the last two decades. Researchers have shown great interest owing to the amazing features of nanofluids including heat transfer and thermal conductivity enhancement capabilities. Having such remarkable features of nanofluids in mind we have envisioned a mathematical model that discusses the flow of nanofluid comprising Nickel-Zinc Ferrite-Ethylene glycol (Ni-ZnFe2O4-C2H6O2) amalgamation past an elongated curved surface with autocatalytic chemical reaction. The additional impacts added to the flow model are the heat generation/absorption with nonlinear thermal radiation. At the boundary, the slip and the convective conditions are added. Pertinent transformations are affianced to get the system of ordinary differential equations from the governing system in curvilinear coordinates. A numerical solution is found by applying MATLAB build-in function bvp4c. Graphical illustrations and the numerically computed estimates are discussed and analyzed properly. It is comprehended that velocity and temperature distributions have varied trends near and away from the curve when the curvature parameter is enhanced. Further, it is comprehended that the concentration field declines for both homogeneous and heterogeneous reaction parameters.