The first cancer patient with COVID-19 in Slovakia

Klin Onkol. 2020 Spring;33(5):386-389. doi: 10.14735/amko2020386.

Abstract

Background: In December 2019 a new strain of coronavirus SARS-CoV-2 has emerged and affected health care worldwide. Patients with cancer and other comorbidities are at increased risk for adverse outcomes in this infection.

Case: In this case report we present a 75-year-old patient with a localized gastric adenocarcinoma, currently treated by perioperative chemotherapy regimen, who had an rT-PCR proven novel coronavirus SARS-CoV-2 infection. Laboratory and radiologic assessments were performed in order to assess disease severity; however, the findings were not altered in accordance with the findings associated with COVID-19 disease.

Results: On the first hospital day the patient had a low grade fever with chills. Subsequently a pharmacological therapy with hydroxychloroquine and azithromycin was started. After pharmacologic and symptomatic treatment, the patient was reassessed for SARS-CoV-2, with negative results. At discharge, the patient was ordered a 14-day mandatory quarantine. After 57 days of follow-up, the patient underwent a new rapid antibody test by Acro Biotech inc., which gave negative results for IgM and IgG.

Conclusion: An infection with SARS-CoV-2 is associated with a more severe disease in patients with comorbidities and cancer; however, this case patient had a mild course of COVID-19 disease. The aim of this case report is to share the information on the clinical course and outcomes of a patient with malignancy. Rapid spreading of information is crucial in the management of COVID-19.

Keywords: COVID-19; Chemotherapy; Gastric cancer; SARS-CoV-2; treatment.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / complications*
  • Aged
  • Azithromycin / administration & dosage
  • Betacoronavirus
  • COVID-19
  • COVID-19 Drug Treatment
  • Coronavirus Infections / complications*
  • Coronavirus Infections / drug therapy
  • Humans
  • Hydroxychloroquine / administration & dosage
  • Male
  • Pandemics
  • Patient Discharge
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / drug therapy
  • SARS-CoV-2
  • Slovakia
  • Stomach Neoplasms / complications*
  • Treatment Outcome

Substances

  • Hydroxychloroquine
  • Azithromycin