Randomized Controlled Trial of Multi-Component Cognitive Stimulation Therapy (SADEM) in Community-Dwelling Demented Adults

J Alzheimers Dis. 2020;78(3):1033-1045. doi: 10.3233/JAD-200574.

Abstract

Background: Dementia is a persistent, progressive state of cognitive decline against which pharmacological intervention has a modest efficacy, reducing behavioral but not cognitive symptoms. Therefore, different non-pharmacological therapies have been developed; the most scientifically recognized are cognitive therapies that have improved cognitive function and daily life activities.

Objective: To evaluate the effectiveness of a multicomponent cognitive stimulation therapy (SADEM) on cognitive and behavioral function and daily life activities in patients with mild stage dementia.

Methods: Controlled clinical trial with pre- and post-intervention (12 months) and follow-up (24 months after) evaluations. Participants (67) diagnosed with mild dementia were randomly assigned to intervention group (n = 39) or control group (n = 28). The intervention took place throughout one year and consisted of two weekly 90-minute sessions and one more a year after a monthly follow-up. Instruments were used to evaluate outcomes in cognitive, behavioral, and affective domains.

Results: The results showed statistically significant differences, with improvement in the cognitive outcomes and the Dementia Index post-intervention (p = 0.01). No progression of the disease was observed at the end of the study.

Conclusion: The multicomponent intervention tested had positive effects on cognitive and behavioral functions and daily life activities in people with mild stage dementia, delaying progression for at least two years.

Keywords: Cognitive stimulation therapy; SADEM; dementia; functional cognition; multicomponent intervention; music therapy.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Attention
  • Cognitive Dysfunction / physiopathology
  • Cognitive Dysfunction / psychology
  • Cognitive Dysfunction / rehabilitation*
  • Dementia / physiopathology
  • Dementia / psychology
  • Dementia / rehabilitation*
  • Disease Progression
  • Female
  • Humans
  • Independent Living
  • Language
  • Male
  • Memory
  • Mexico
  • Neurological Rehabilitation
  • Severity of Illness Index