Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report

Satoshi Okuda; Ken-Ichi Tabata; Soichiro Shimura; Takahiro Harano; Izuru Shiba; Masatsugu Iwamura

doi:10.1016/j.eucr.2020.101315

Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report

Urol Case Rep. 2020 Jun 23:33:101315. doi: 10.1016/j.eucr.2020.101315. eCollection 2020 Nov.

Authors

Satoshi Okuda¹, Ken-Ichi Tabata¹, Soichiro Shimura¹, Takahiro Harano¹, Izuru Shiba¹, Masatsugu Iwamura¹

Affiliation

¹ Department of Urology, Kitasato University School of Medicine, Kanagawa, Japan.

Abstract

Localized treatment has recently become an option for treating oligometastatic prostate cancer. Metastasis-directed therapy (MDT) is a new approach for localized treatment, and many clinical trials are ongoing. In the present case, biochemical recurrence occurred 8 months after a radical prostatectomy for localized prostate cancer, and oligometastases were diagnosed via whole-body magnetic resonance imaging. Metastasis-directed radiotherapy (MDRT) was performed on all oligometastatic sites. After MDRT without androgen deprivation therapy, the prostate-specific antigen (PSA) decreased to an undetectable level and did not increase for 24 months.

Keywords: Metastasis-directed therapy; Oligometastasis; Prostate cancer; Whole-body magnetic resonance imaging.

Publication types

Case Reports