Characteristics and evaluation of the effectiveness of monitoring and control measures for the first 69 Patients with COVID-19 from 18 January 2020 to 2 March in Wuxi, China

Ping Shi; Yumeng Gao; Yuan Shen; Enping Chen; Hai Chen; Juan Liu; Yujun Chen; Yong Xiao; KeWei Wang; Chao Shi; Bing Lu

doi:10.1016/j.scs.2020.102559

Characteristics and evaluation of the effectiveness of monitoring and control measures for the first 69 Patients with COVID-19 from 18 January 2020 to 2 March in Wuxi, China

Sustain Cities Soc. 2021 Jan:64:102559. doi: 10.1016/j.scs.2020.102559. Epub 2020 Oct 17.

Authors

Ping Shi¹, Yumeng Gao¹, Yuan Shen¹, Enping Chen¹, Hai Chen¹, Juan Liu¹, Yujun Chen¹, Yong Xiao², KeWei Wang³, Chao Shi¹, Bing Lu¹

Affiliations

¹ Department of Disease Control, Wuxi Center for Disease Control and Prevention, No. 499 Jin Cheng Road, Wuxi 214023, Jiangsu Province, China.
² Laboratory, Wuxi Center for Disease Control and Prevention, No. 499 Jin Cheng Road, Wuxi 214023, Jiangsu Province, China.
³ Department of Hospital Infection, Affiliated Hospital of Jiangnan University, No. 299 Qing Yang Road, Wuxi 214023, Jiangsu Province, China.

Abstract

Background: The Coronavirus disease (COVID-19) has caused 91,305 confirmed cases and 4746 deaths in China by 13:50 on October 11, 2020. We analyzed data on 69 infections in Wuxi to describe the disease's characteristics, to analyze factors of cases clinical outcome and to evaluate the prevention and control measures.

Methods: The demographic characteristics, exposure history, time indicators and propagation dynamics in Wuxi were collected.

Results: The clinical severity of cases was mostly mild and normal (75.36 %). Aging (relative risk [RR] = 1.04, 95 % confidence interval [CI]: 1.001-1.08) and fever (RR = 10.33, 95 %CI: 2.75-38.78) were risk factors for disease severity. The mean incubation period was estimated to be 4.77 days (95 % CI: 3.61-5.94), with a mean serial interval of 6.31 days (95 % CI: 5.12-7.50). The controlled reproduction number was estimated to be 1.12 (95 %CI: 0.71-1.69).

Conclusions: The incidence of COVID-19 in Wuxi has turned into a lower level, suggesting the early prevention and control measures have achieved effectiveness. Aging and fever of initial symptom were risk factors for severe clinical outcome. The family clusters provided further clues of the risk factors for COVID-19 transmission.

Keywords: COVID-19; Characteristics; Propagation dynamics; Risk factors; Time indicators.