Lymphomatoid papulosis subtype C: A case report and literature review

Dermatol Ther. 2021 Jan;34(1):e14452. doi: 10.1111/dth.14452. Epub 2020 Nov 3.

Abstract

Lymphomatoid papulosis (LyP) is a rare CD30+ lymphoproliferative primary skin disease with a benign clinical course and malignant histopathology. LyP is classified into seven subtypes based on histopathology: subtypes A through F and LyP with 6p25.3 chromosome rearrangement. We present here, a case report of a 51-year-old man, afflicted with multiple papules and nodules on his left arm for over 3 months and diagnosed with LyP subtype C. The patient refused treatment, and his lesions faded with no visible rash on the left arm 14 months after diagnosis.

Keywords: CD30+ lymphoproliferative disorders; cutaneous T-cell lymphoma; lymphomatoid papulosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Exanthema*
  • Humans
  • Ki-1 Antigen
  • Lymphomatoid Papulosis* / diagnosis
  • Lymphomatoid Papulosis* / genetics
  • Male
  • Middle Aged
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / genetics

Substances

  • Ki-1 Antigen