Third bariatric procedure for insufficient weight loss or weight regain: how far should we go?

Surg Obes Relat Dis. 2021 Jan;17(1):96-103. doi: 10.1016/j.soard.2020.08.032. Epub 2020 Sep 1.

Abstract

Background: Revisional procedures in bariatric surgery are increasing with several debated failure risk factors, such as super obesity and old age. No study has yet evaluated the outcomes and risks of a third bariatric procedure indicated for weight loss failure or weight regain.

Objectives: To assess failure risks of a third bariatric procedure according to Reinhold's criteria (percentage excess weight loss [%EWL] ≤50% and/or body mass index [BMI] ≥35 kg/m2).

Setting: A university-affiliated tertiary care center, France.

Methods: From 2009 to 2019, clinical data and weight loss results of patients who benefited from 3 bariatric procedures for weight loss failure or weight regain were collected prospectively and analyzed using a binary logistic regression. Weight loss failure was defined according to Reinhold's criteria.

Results: Among 1401 bariatric procedures performed, 336 patients benefited from 2 or more procedures, and 45 had a third surgery. Eleven patients that were reoperated on because of malnutrition or gastroesophageal reflux disease were excluded from the final analysis. Among 34 patients with 3 procedures because of weight loss failure or regain, mean BMI was 48.3 ± 8.3 kg/m2, and mean age was 30 ± 10.7 years. Three out of 34 patients (9%) presented a severe complication (Dindo-Clavien IIIb) and 2 (6%) had a minor one. Achieving Reinhold's weight loss criteria after the second bariatric procedure was a significant predictor of success of the third procedure (β = 2.9 ± 1.3 S.E.).

Conclusion: Not reaching Reinhold's criteria after a second bariatric procedure was identified as a significant risk factor of failure of a third procedure. A third surgery should be carefully discussed especially in case of primary failure of previous procedures.

Keywords: Bariatric surgery; Obesity; Revisional surgery; Third bariatric procedure; Weight loss failure.

MeSH terms

  • Adult
  • Bariatric Surgery*
  • France
  • Humans
  • Laparoscopy*
  • Obesity, Morbid* / surgery
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome
  • Weight Gain
  • Weight Loss
  • Young Adult