Blast cells in acute megakaryoblastic leukaemia with Down syndrome are characterized by low CLEC12A expression

Br J Haematol. 2021 Jan;192(1):e7-e11. doi: 10.1111/bjh.17122. Epub 2020 Oct 23.
No abstract available

Keywords: CD96; CLEC12A; Down syndrome; TIM3; acute megakaryoblastic leukemia.

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Marrow / pathology
  • Child
  • Down Syndrome / complications
  • Down Syndrome / pathology*
  • Female
  • Humans
  • Lectins, C-Type / analysis*
  • Leukemia, Megakaryoblastic, Acute / complications
  • Leukemia, Megakaryoblastic, Acute / pathology*
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes / complications
  • Myelodysplastic Syndromes / pathology
  • Prospective Studies
  • Receptors, Mitogen / analysis*
  • Young Adult

Substances

  • CLEC12A protein, human
  • Lectins, C-Type
  • Receptors, Mitogen