Inter-individual variation in CYP2A6 activity and chronic obstructive pulmonary disease in smokers: Perspectives for an early predictive marker

Biochim Biophys Acta Mol Basis Dis. 2021 Jan 1;1867(1):165990. doi: 10.1016/j.bbadis.2020.165990. Epub 2020 Oct 19.
No abstract available

Keywords: COPD; CYP2A6; Chronic obstructive pulmonary disease; Nicotine metabolite ratio.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cytochrome P-450 CYP2A6 / genetics*
  • Cytochrome P-450 CYP2A6 / metabolism
  • Female
  • Genetic Variation*
  • Humans
  • Male
  • Pulmonary Disease, Chronic Obstructive / enzymology
  • Pulmonary Disease, Chronic Obstructive / etiology
  • Pulmonary Disease, Chronic Obstructive / genetics*
  • Smokers
  • Smoking / adverse effects
  • Smoking / genetics*

Substances

  • CYP2A6 protein, human
  • Cytochrome P-450 CYP2A6