Disseminated histoplasmosis in a cat rescued in Fortaleza, Brazil, and successfully treated with itraconazole - First case report identified molecularly

Liliane Lima da Silva Lomônaco; Stefanie Bressan Waller; Marlete Brum Cleff; Angelita Dos Reis Gomes; Barbara Wilka Leal Silva; Rosane de Oliveira Cruz; Talles Monte de Almeida; Amanda Leal de Vasconcellos; Wesley Lyeverton Correia Ribeiro; Renata Osório de Faria; Mário Carlos Araújo Meireles; Adriana de Queiroz Pinheiro; Paula Priscila Correia Costa

doi:10.1016/j.mmcr.2020.09.005

Disseminated histoplasmosis in a cat rescued in Fortaleza, Brazil, and successfully treated with itraconazole - First case report identified molecularly

Med Mycol Case Rep. 2020 Oct 2:30:29-34. doi: 10.1016/j.mmcr.2020.09.005. eCollection 2020 Dec.

Authors

Liliane Lima da Silva Lomônaco¹, Stefanie Bressan Waller², Marlete Brum Cleff², Angelita Dos Reis Gomes², Barbara Wilka Leal Silva¹, Rosane de Oliveira Cruz¹, Talles Monte de Almeida¹, Amanda Leal de Vasconcellos³, Wesley Lyeverton Correia Ribeiro⁴, Renata Osório de Faria², Mário Carlos Araújo Meireles², Adriana de Queiroz Pinheiro³, Paula Priscila Correia Costa^{2

3}

Affiliations

¹ Veterinarian Autonomous, Fortaleza/CE, Brazil.
² Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil.
³ Faculty of Veterinary, Ceará State University, Av. Dr. Silas Munguba, 1700, Campus Do Itaperi, Fortaleza/CE, 60714-903, Brazil.
⁴ Department of Physiology and Pharmacology, Federal University of Ceará, Rua Cel. Nunes de Melo, 1127, Rodolfo Teófilo, Fortaleza/CE, 6430-275, Brazil.

Abstract

An unneutered female cat of unknown age presented bloody lesions on the edematous face, and respiratory signs. Cytology and culture from the skin sample collected with fine-needle aspiration showed yeasts inside activated macrophages, and fungal growth characteristic of Histoplasma spp., which was molecularly confirmed that was Histoplasma capsulatum var. capsulatum. The cat was successfully treated with oral itraconazole (10 mg/kg/daily) for 120 days. This is the first case report of feline histoplasmosis confirmed molecularly in Brazil.

Publication types

Case Reports