Noninvasive prenatal testing detected acute myeloid leukemia in paucisymptomatic pregnant patient

Laura Yissel Rengifo; Lucienne Michaux; Johan Maertens; Thomas Tousseyn; Liesbeth Lenaerts; Joris Robert Vermeesch; Peter Vandenberghe; Barbara Dewaele

doi:10.1002/ccr3.3027

Noninvasive prenatal testing detected acute myeloid leukemia in paucisymptomatic pregnant patient

Clin Case Rep. 2020 Jun 20;8(10):1924-1927. doi: 10.1002/ccr3.3027. eCollection 2020 Oct.

Authors

Laura Yissel Rengifo¹, Lucienne Michaux¹, Johan Maertens^{2

3}, Thomas Tousseyn⁴, Liesbeth Lenaerts⁵, Joris Robert Vermeesch¹, Peter Vandenberghe^{1

3}, Barbara Dewaele¹

Affiliations

¹ Center for Human Genetics University Hospitals Leuven Leuven Belgium.
² Department of Microbiology and Immunology KU Leuven Leuven Belgium.
³ Department of Hematology University Hospitals Leuven Leuven Belgium.
⁴ Department of Pathology University Hospitals Leuven Leuven Belgium.
⁵ Department of Oncology KU Leuven Leuven Belgium.

Abstract

To the authors' best knowledge, this is the first report of acute myeloid leukemia (AML) detected by noninvasive prenatal testing. This was an aggressive case that otherwise would have been difficult to characterize due to disadvantages of "gold-standard" techniques.

Keywords: acute myeloid leukemia; bone marrow dry tap; hematology; incidental finding; malignancy; noninvasive prenatal testing.

Publication types

Case Reports