Garcin Syndrome Due to Meningeal Carcinomatosis from Gastric Cancer

Intern Med. 2021 Mar 15;60(6):855-858. doi: 10.2169/internalmedicine.5797-20. Epub 2020 Oct 21.

Abstract

A 58-year-old woman presented to our hospital with complaints of dysphagia. Esophagogastroduodenoscopy showed an esophagogastric junction tumor with multiple duodenal intramural metastases, and computed tomography showed peritoneal metastasis. In the middle of her fourth cycle of chemotherapy, she displayed symptoms of a left-sided multi-cranial nerve palsy. She was diagnosed with Garcin syndrome caused by meningeal carcinomatosis from gastric cancer based on the results of gadolinium-enhanced brain magnetic resonance imaging and cytology of the cerebrospinal fluid. It is important not to overlook meningeal irritation symptoms or paralysis of cranial nerves and to consider the possibility of Garcin syndrome caused by meningeal carcinomatosis.

Keywords: garcin syndrome; gastric cancer; meningeal carcinomatosis.

Publication types

  • Case Reports

MeSH terms

  • Cranial Nerve Diseases*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Meningeal Carcinomatosis* / complications
  • Meningeal Carcinomatosis* / diagnosis
  • Meningeal Neoplasms*
  • Middle Aged
  • Stomach Neoplasms* / complications
  • Stomach Neoplasms* / diagnosis
  • Tomography, X-Ray Computed