Adult Medulloblastoma Depicted With 99mTc-HYNIC-[D-Phe1, Tyr3-Octreotide] SPECT/CT

Clin Nucl Med. 2020 Dec;45(12):1001-1002. doi: 10.1097/RLU.0000000000003341.

Abstract

Although medulloblastoma constitutes the second most common malignant brain tumor in children, it encountered very rarely in adults. The incidence of adult medulloblastoma is approximately 0.6 to 1 case per million. It accounts for less than 1% of adult brain tumors and is located most commonly at the posterior cranial fossa. We present an extremely rare case of a 67-year-old man with cerebellar medulloblastoma with residual disease after surgery, chemotherapy, and radiation therapy, depicted with Tc-HYNIC-[D-Phe, Tyr-Octreotide] SPECT/CT. Somatostatin receptor scintigraphy was performed for staging and for the possibility of treatment with somatostatin analogs or peptide radionuclide therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebellar Neoplasms / diagnostic imaging*
  • Cerebellar Neoplasms / metabolism
  • Cerebellar Neoplasms / pathology
  • Humans
  • Male
  • Medulloblastoma / diagnostic imaging*
  • Medulloblastoma / metabolism
  • Medulloblastoma / pathology
  • Neoplasm Staging
  • Octreotide / analogs & derivatives*
  • Organotechnetium Compounds*
  • Receptors, Somatostatin / metabolism
  • Single Photon Emission Computed Tomography Computed Tomography*

Substances

  • Organotechnetium Compounds
  • Receptors, Somatostatin
  • technetium Tc 99m-tricine-hydrazinonicotinyl-Phe(1)-Tyr(3)-octreotide
  • Octreotide