Between-group difference in mean values or changes in pain intensity? Evaluating the distribution of change from baseline in a neuropathic cancer pain clinical trial
Ann Palliat Med. 2020 Nov;9(6):4398-4402.
doi: 10.21037/apm-20-930.
Epub 2020 Oct 21.
1 Department of Psychosomatic Medicine, Faculty of Medicine, Kindai University, Osaka, Japan; Palliative Care Center, Faculty of Medicine, Kindai University, Osaka, Japan; National Cancer Center Hospital, Tokyo, Japan; Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia. hiromima@ncc.go.jp.
2 Palliative and Supportive Care Division, Seirei Mikatahara General Hospital, Hamamatsu, Japan.
3 Japanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan.
4 Division of Biostatistics, Graduate School of Medicine, Tohoku University, Sendai, Japan.
5 Department of Psychosomatic Medicine, Faculty of Medicine, Kindai University, Osaka, Japan; Palliative Care Center, Faculty of Medicine, Kindai University, Osaka, Japan.