DNA Damage Repair Deficiency and Synthetic Lethality for Cancer Treatment

Trends Mol Med. 2021 Jan;27(1):91-92. doi: 10.1016/j.molmed.2020.09.011. Epub 2020 Oct 16.
No abstract available

Keywords: PARP inhibitor; alternative DNA repair pathways; homologous recombination repair.

MeSH terms

  • DNA Damage*
  • DNA Repair*
  • Disease Management
  • Genetic Predisposition to Disease
  • Humans
  • Neoplasms / genetics*
  • Neoplasms / therapy*
  • Synthetic Lethal Mutations*