The Binns Program for Cord Blood Research: A novel model of cord blood banking for academic biomedical research

Sruthi Mantri; Adam Sheikali; Corey Binns; Deirdre J Lyell; David L DiGiusto; Matthew H Porteus; Rajni Agarwal-Hashmi

doi:10.1016/j.placenta.2020.10.018

The Binns Program for Cord Blood Research: A novel model of cord blood banking for academic biomedical research

Placenta. 2021 Jan 1:103:50-52. doi: 10.1016/j.placenta.2020.10.018. Epub 2020 Oct 13.

Authors

Sruthi Mantri¹, Adam Sheikali², Corey Binns³, Deirdre J Lyell⁴, David L DiGiusto⁵, Matthew H Porteus⁶, Rajni Agarwal-Hashmi⁷

Affiliations

¹ Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: sruthim@stanford.edu.
² Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: adamsheikali1995@gmail.com.
³ Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: coreybinns@gmail.com.
⁴ Division of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address: dlyell@stanford.edu.
⁵ Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: digiustoconsulting@gmail.com.
⁶ Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: mporteus@stanford.edu.
⁷ Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. Electronic address: rajnia@stanford.edu.

PMID: 33075720
DOI: 10.1016/j.placenta.2020.10.018

Abstract

Umbilical cord blood is an important graft source in the treatment of many genetic, hematologic, and immunologic disorders by hematopoietic stem cell transplantation. Millions of cord blood units have been collected and stored for clinical use since the inception of cord blood banking in 1989. However, the use of cord blood in biomedical research has been limited by access to viable samples. Here, we present a cost-effective, self-sustaining model for the procurement of fresh umbilical cord blood components for research purposes within hospital-affiliated academic institutions.

Keywords: Cord blood banking; Hematopoietic stem cell; The Binns Program; Umbilical cord; Umbilical cord blood.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Academies and Institutes / economics
Academies and Institutes / organization & administration
Academies and Institutes / standards
Biomedical Research / economics
Biomedical Research / methods
Biomedical Research / organization & administration*
Biomedical Research / standards
Blood Banks / economics
Blood Banks / organization & administration*
Blood Banks / standards
Blood Specimen Collection / economics
Blood Specimen Collection / methods
Blood Specimen Collection / standards
California
Cost-Benefit Analysis
Female
Fetal Blood* / cytology
Fetal Blood* / transplantation
Hematopoietic Stem Cell Transplantation / economics
Hematopoietic Stem Cell Transplantation / methods
Hematopoietic Stem Cell Transplantation / standards
Humans
Infant, Newborn
Models, Organizational*
Pregnancy