Comparative Study on the Efficacy of Postsurgical Oral Prophylactic Antibiotic Versus Antimicrobial Suture Placement Alone in Preventing Surgical Site Infection After Removal of Impacted Mandibular Third Molar

Shama Mohan; B S Jayanth; Shruthi Saralaya; S M Sunil; A S Mohamed Sageer; R Harikrishnan

doi:10.1007/s12663-019-01267-0

Comparative Study on the Efficacy of Postsurgical Oral Prophylactic Antibiotic Versus Antimicrobial Suture Placement Alone in Preventing Surgical Site Infection After Removal of Impacted Mandibular Third Molar

J Maxillofac Oral Surg. 2020 Dec;19(4):546-551. doi: 10.1007/s12663-019-01267-0. Epub 2019 Aug 2.

Authors

Shama Mohan¹, B S Jayanth¹, Shruthi Saralaya¹, S M Sunil¹, A S Mohamed Sageer¹, R Harikrishnan¹

Affiliation

¹ Department of Oral and Maxillofacial Surgery, Coorg Institute of Dental Sciences, Virajpet, Karnataka India.

Abstract

Aim: To evaluate the efficacy of postsurgical oral prophylactic antibiotic versus antimicrobial suture placement in preventing infection after removal of an impacted mandibular third molar.

Materials and methods: This was a prospective, single-blind study including 150 individuals of 18-40 years divided into two groups with 75 patients each. The patients in Group 1 were administered oral amoxicillin tablets 500 mg for 5 days postsurgery with 3-0 polyglactin sutures for closure and in group 2 with (3-0) antimicrobial chlorhexidine diacetate-impregnated polyglactin sutures only. Evaluation was done on 3rd, 7th, 15th days and 1 month.

Results: There was no significant difference in rates of infection between the groups. Abnormal erythema, pain and trismus showed statistically better results in group 2 on 3rd and 7th days. An antibiotic side effect assessment showed 17.65% patients with minor side effects.

Conclusion: Chlorhexidine diacetate-impregnated polyglactin sutures showed reduced erythema, pain and trismus in healthy patients undergoing surgical removal of third molar.

Keywords: Antibiotic side effect assessment; Chlorhexidine diacetate-impregnated polyglactin suture; Erythema; Infection; Postsurgical antibiotic prophylaxis; Trismus.