Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes

Int Rev Cell Mol Biol. 2020:356:99-130. doi: 10.1016/bs.ircmb.2020.07.001. Epub 2020 Sep 9.
No abstract available

Keywords: Actin cytoskeleton; Cancer; Exosomes; Granzymes; Immune evasion; Immunological synapse; Lysosomes; Perforin; Vesicle trafficking.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Actin Cytoskeleton / immunology*
  • Actin Cytoskeleton / pathology
  • Actins / immunology*
  • Animals
  • Humans
  • Immunological Synapses / immunology*
  • Immunological Synapses / pathology
  • Neoplasm Proteins / immunology*
  • T-Lymphocytes, Cytotoxic / immunology*
  • T-Lymphocytes, Cytotoxic / pathology
  • Tumor Escape*

Substances

  • Actins
  • Neoplasm Proteins