From 1957 to Nowadays: A Brief History of Epigenetics

Int J Mol Sci. 2020 Oct 14;21(20):7571. doi: 10.3390/ijms21207571.

Abstract

Due to the spectacular number of studies focusing on epigenetics in the last few decades, and particularly for the last few years, the availability of a chronology of epigenetics appears essential. Indeed, our review places epigenetic events and the identification of the main epigenetic writers, readers and erasers on a historic scale. This review helps to understand the increasing knowledge in molecular and cellular biology, the development of new biochemical techniques and advances in epigenetics and, more importantly, the roles played by epigenetics in many physiological and pathological situations.

Keywords: DNA methylation; epigenetics; epitranscriptomics; histones; history.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • DNA Methylation
  • Epigenesis, Genetic*
  • Epigenomics / history*
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Protein Processing, Post-Translational