Asymptomatic severe aortic stenosis, bicuspid aortic valves and moderate aortic stenosis in heart failure: New indications for transcatheter aortic valve implantation

Michel Pompeu B O Sá; Matheus Simonato; Jef Van den Eynde; Luiz Rafael P Cavalcanti; Leonardo Roever; Gianluigi Bisleri; Aleksander Dokollari; Danny Dvir; Konstantin Zhigalov; Arjang Ruhparwar; Alexander Weymann

doi:10.1016/j.tcm.2020.10.002

Asymptomatic severe aortic stenosis, bicuspid aortic valves and moderate aortic stenosis in heart failure: New indications for transcatheter aortic valve implantation

Trends Cardiovasc Med. 2021 Oct;31(7):435-445. doi: 10.1016/j.tcm.2020.10.002. Epub 2020 Oct 13.

Affiliations

¹ Division of Cardiovascular Surgery, Pronto Socorro Cardiológico de Pernambuco - PROCAPE, University of Pernambuco, Pernambuco, Brazil.
² Division of Cardiac Surgery, Escola Paulista de Medicina - UNIFESP, São Paulo, Brazil.
³ Department of Cardiovascular Diseases, Research Unit of Cardiac Surgery, University Hospitals Leuven, and Department of Cardiovascular Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address: jef.vandeneynde@student.kuleuven.be.
⁴ Department of Clinical Research, Federal University of Uberlândia, Minas Gerais, Brazil.
⁵ Division of Cardiac Surgery, Queen's University, Toronto, Canada.
⁶ Division of Cardiac Surgery, University of Toronto, Toronto, Canada.
⁷ Division of Cardiology, University of Washington, Washington, United States of America.
⁸ Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, Essen, Germany.

PMID: 33065313
DOI: 10.1016/j.tcm.2020.10.002

Abstract

Aortic stenosis (AS) remains one of the most common valvular heart diseases, with enormous impact on patient survival. Over the past years, transcatheter aortic valve implantation (TAVI) has become a reality worldwide, offering a less invasive method to treat AS. Apart from the classical indications for aortic valve disease, recent studies tried to address unanswered questions for TAVI - asymptomatic severe AS, bicuspid aortic valves and moderate AS in patients with heart failure. This review discusses the rationale of those possible indications, pitfalls and current evidence in the medical literature.

Keywords: Aortic stenosis; Aortic valve; Bicuspid aortic valve; Heart failure; TAVI.

Publication types

Review

MeSH terms

Aortic Valve / diagnostic imaging
Aortic Valve / surgery
Aortic Valve Stenosis* / diagnostic imaging
Aortic Valve Stenosis* / surgery
Bicuspid Aortic Valve Disease*
Heart Failure* / diagnosis
Heart Failure* / etiology
Heart Failure* / therapy
Heart Valve Prosthesis*
Humans
Transcatheter Aortic Valve Replacement* / adverse effects
Treatment Outcome