Increasing Incidence of Microscopic Colitis in a Population-Based Cohort Study in Switzerland

Hugo Maye; Ekaterina Safroneeva; Sébastien Godat; Christine Sempoux; Pu Yan; Hanifa Bouzourène; Walter Seelentag; Edouard Stauffer; Lorenzo Taminelli; Frank Seibold; Alain M Schoepfer

doi:10.1016/j.cgh.2020.10.015

Increasing Incidence of Microscopic Colitis in a Population-Based Cohort Study in Switzerland

Clin Gastroenterol Hepatol. 2021 Oct;19(10):2205-2206. doi: 10.1016/j.cgh.2020.10.015. Epub 2020 Oct 14.

Authors

Affiliations

¹ Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
² Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
³ Institute of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
⁴ Argot Laboratoire SA, Lausanne, Switzerland.
⁵ Unilabs Laboratoire SA, Lausanne, Switzerland.
⁶ Institut de Pathologie Romand, Lonay, Switzerland.
⁷ Promed Laboratoire SA, Marly, Switzerland.
⁸ Aurigen Laboratoire SA, Lausanne, Switzerland.
⁹ Cabinet de Gastroentérologie, Balsiger, Seibold & Partenaires, Villars-sur-Glâne, Fribourg, Switzerland.
¹⁰ Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland. Electronic address: alain.schoepfer@chuv.ch.

PMID: 33065310
DOI: 10.1016/j.cgh.2020.10.015

Abstract

Microscopic colitis (MC) is a chronic inflammatory disease of the colon that presents with chronic, nonbloody watery diarrhea and only few or no endoscopic abnormalities. Histologic examination discriminates lymphocytic colitis (LyC; presence of ≥20 intraepithelial lymphocytes per 100 surface epithelial cells) and collagenous colitis (CC; colonic subepithelial collagen band >10 μm in diameter).¹^,² MC not otherwise specified describes a subgroup of patients who do not fulfill the diagnostic criteria for either CC or LyC.¹^,² Population-based epidemiologic data regarding MC are scarce. We aimed to evaluate the clinical presentation at diagnosis, incidence, and prevalence of MC in Cantons of Vaud and Fribourg, Switzerland.

MeSH terms

Cohort Studies
Colitis*
Colitis, Collagenous*
Colitis, Lymphocytic*
Colitis, Microscopic* / diagnosis
Colitis, Microscopic* / epidemiology
Humans
Incidence
Switzerland / epidemiology