Madagascar 2018-2019 measles outbreak response: main strategic areas

Pan Afr Med J. 2020 Sep 5:37:20. doi: 10.11604/pamj.2020.37.20.24530. eCollection 2020.

Abstract

Introduction: on October 4th, 2018, a measles outbreak was declared in Madagascar. This study describes the outbreak response in terms of coordination, case management, vaccination response and epidemiological surveillance.

Methods: data were collected using a line list and vaccination tally sheet. Serum samples were collected within 30 days of rash onset for laboratory testing; confirmation was made by detection of measles immunoglobulin M antibody.

Results: from September 2018 to May 2019, a total of 146,277 measles cases were reported which included 1394 (1%) laboratory-confirmed cases and 144,883 (99%) epidemiological link-confirmed cases. The outbreak affected equally males (72,917 cases; 49.85%) and females (73,233 cases; 50.06%). The sex was not specified for 127 (0.09%) cases. Case fatality rate and attack rate were high among children less than 5 years. Responses interventions include effective coordination, free of charge case management, reactive vaccination, strengthened real-time surveillance, communication and community engagement and the revitalization of the routine immunization. Reactive vaccination was implemented in different phases. A total of 7,265,990 children aged from 6 months to 9 years were vaccinated. Post campaign survey coverage was 95%, 96% and 97% for phase 1, 2, 3 respectively.

Conclusion: elimination of measles will be challenging in Madagascar because of low routine immunization coverage and the absence of a second dose of measles vaccine in the routine immunization schedule.

Keywords: Madagascar; Measles; outbreak response.

MeSH terms

  • Child
  • Child, Preschool
  • Disease Outbreaks / prevention & control*
  • Epidemiological Monitoring
  • Female
  • Humans
  • Immunization Programs
  • Immunization Schedule
  • Immunoglobulin M / blood
  • Infant
  • Madagascar
  • Male
  • Measles / epidemiology
  • Measles / prevention & control*
  • Measles Vaccine / administration & dosage*
  • Vaccination / statistics & numerical data*
  • Vaccination Coverage

Substances

  • Immunoglobulin M
  • Measles Vaccine