Transvaginal natural orifice endoscopic surgery for extremely obese patients with early-stage endometrial cancer

J Obstet Gynaecol Res. 2021 Jan;47(1):262-269. doi: 10.1111/jog.14509. Epub 2020 Oct 15.

Abstract

Aim: The purpose of this study was to assess the feasibility and efficacy of transvaginal natural orifice transluminal endoscopic surgery (v-NOTES) staging surgery for extreme obese patients with early-stage type-1 endometrial cancer.

Methods: Study included cases of extreme obese patients with early-stage endometrial cancer who underwent v-NOTES between January 2019 and June 2019 at a tertiary referral medical center. The following parameters were noted: patient age, body mass index (BMI), operating time, conversion to conventional laparoscopy or laparotomy, any intraoperative or postoperative complications, estimated blood loss, pre- and postoperative hemoglobin levels, postoperative pain scores of the patients using visual analogue scale (VAS) at 6th, 12th and 24th h, length of hospital stay and final pathology report.

Results: Six cases of extreme obese patients with early-stage endometrial cancer underwent hysterectomy and bilateral salpingo-oophorectomy via the transvaginal NOTES. These six patients had a mean body mass index of 51.4 kg/m2 (SD = 6,13). No conversion to conventional laparoscopy or even laparotomy was needed in any of these patients. No adjuvant therapy was needed since all of the patients had early-stage endometrial carcinoma.

Conclusion: Given the increased risk of surgical morbidity and mortality associated with increasing BMI, it is paramount importance to establish safe surgical approaches to gynecological pathologies. We think that v-NOTES offers greater benefit to obese patients when performed by an experienced surgeon and v-NOTES is a safe, effective and feasible minimally invasive surgery in extreme obese patients with early endometrial cancer.

Keywords: early-stage endometrial cancer; extreme obesity; transvaginal NOTES.

MeSH terms

  • Endometrial Neoplasms* / surgery
  • Female
  • Humans
  • Hysterectomy
  • Laparoscopy*
  • Natural Orifice Endoscopic Surgery*
  • Obesity / complications