Dens invaginatus is an anomaly mostly observed in maxillary incisors. This study aimed to assess the prevalence of dens invaginatus in maxillary incisors in young Israeli population and to study its potential association with clinical coronal morphological features. Data was collected from periapical radiographs and clinical photographs of patients from Orthodontics Department between 2006 and 2018. Radiographic characteristics were evaluated and compared to clinical coronal morphological features. Statistical analysis was performed using the Pearson chi-square test with statistical significance set at p < 0.05. The sample included 1621 maxillary incisors from 547 patients. Dens invaginatus was observed in 422 (26%) of these teeth. Maxillary lateral incisors were more affected than central incisors. In 103 patients dens invaginatus was unilateral, while in all other cases it was bilateral. Unique clinical morphological characteristics were observed in 88% of the teeth that exhibited radiographic evidence of dens invaginatus. Dens invaginatus Type I was most frequently observed, accounting for 90% of the teeth. A significant association between clinical coronal morphological features and dens invaginatus was detected. Dens invaginatus is common in maxillary incisors of the study population. Several clinical morphological features may predict the presence of dens invaginatus.