The social and clinical impact of the COVID-19 epidemic on the Strasbourg lung transplant cohort: A single-center retrospective cohort study

Clin Transplant. 2020 Dec;34(12):e14119. doi: 10.1111/ctr.14119. Epub 2020 Oct 26.

Abstract

The clinical and social impacts of the COVID-19 epidemic on lung transplant (LTx) recipients remain poorly known. We aimed to evaluate its social, clinical, and behavioral consequences on the LTx patients followed in Strasbourg university hospital. A questionnaire was used to collect details concerning patients' lifestyles, their protection methods used to avoid COVID-19 contamination, and clinical infection-related information for March 2020. A specific score was created to quantify patients' contacts and the associated risk of infectious contagion. Data were collected from 322 patients (91.2%). A majority reported a higher application than usual of social distancing and barrier measures. 43.8% described infectious-related symptoms and 15.8% needed an anti-infective treatment. There was no difference in symptom onset according to age, native lung disease, diabetes, or obesity. Nineteen patients were tested for COVID-19, and four were diagnosed positive, all with a favorable outcome. The infection risk contact score was higher for symptomatic patients (p: 0.007), those needing extra-medical appointments (p < .001), and those receiving anti-infective treatments (p = .02). LTx patients reported a careful lifestyle and did not seem at higher risk for COVID-19. Our score showed encouraging preliminary results and could become a useful tool for the usual infection-related follow-up of the LTx patients.

Keywords: COVID-19; lifestyle factors; lung transplantation; protective measures.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology
  • COVID-19 / etiology*
  • COVID-19 / prevention & control
  • Contact Tracing
  • Epidemics
  • Female
  • France / epidemiology
  • Health Behavior*
  • Hospitals, University
  • Humans
  • Life Style
  • Lung Transplantation*
  • Male
  • Middle Aged
  • Patient Compliance / psychology
  • Patient Compliance / statistics & numerical data
  • Physical Distancing
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / epidemiology
  • Postoperative Complications* / prevention & control
  • Postoperative Complications* / psychology
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Social Determinants of Health*
  • Transplant Recipients / psychology*
  • Young Adult