Extricating the Association Between the Prognostic Factors of Colorectal Cancer

J Gastrointest Cancer. 2021 Sep;52(3):1022-1028. doi: 10.1007/s12029-020-00535-4. Epub 2020 Oct 13.

Abstract

Purpose: Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with haematological examinations and tumour demographic characterisations in patients.

Methods: The present investigation is carried out on clinically acknowledged sixty-five CRC patients based on haematological findings and are sorted into stages using TNM and Dukes. The present study is to find the association between haematological findings, demographic characters, differentiation position, lymph node invasion and tumour node metastasis in CRC patients in accordance with their age.

Results: We observed significant (p < 0.05) nexus between lymph node metastasis and tumour node metastasis on the basis of tumour's differentiation demographic positioning and age of the individuals.

Conclusion: Earlier location tracing and medicinal treatment or surgery lessen the chance of CRC morbidity and mortality along with prolonging survival rate via prognostic factors and disease position determination.

Keywords: Colorectal cancer; Haematology; Lymph node metastasis; Staging.

MeSH terms

  • Adult
  • Aged
  • Colorectal Neoplasms / blood
  • Colorectal Neoplasms / epidemiology*
  • Colorectal Neoplasms / pathology*
  • Female
  • Humans
  • India / epidemiology
  • Lymphatic Metastasis / pathology
  • Male
  • Middle Aged
  • Neoplasm Grading / statistics & numerical data*
  • Neoplasm Staging / statistics & numerical data*
  • Prognosis
  • Risk Factors