Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report

J Int Med Res. 2020 Oct;48(10):300060520949410. doi: 10.1177/0300060520949410.

Abstract

Most cases of female genital tuberculosis (TB) are asymptomatic and are thus difficult to diagnose. Coexistence of genital TB and ovarian serous cystadenofibroma (OSCAF) is rare and easily ignored or misdiagnosed. We report a 26-year-old woman with coexistence of genital TB and OSCAF, and with an adnexal mass detected by B-ultrasound. Laparoscopic biopsy of diffuse miliary white nodules was performed on the surface of the peritoneum and both fallopian tubes. Right ovarian cystectomy was performed. Postoperative pathology showed that the right ovarian mass was a benign serous cystadenofibroma, and both fallopian tubes and miliary white nodules on the surface of pelvic organs showed chronic granulomatous inflammation. Polymerase chain reaction for Mycobacterium tuberculosis and acid-fast bacilli culture were positive in biopsies of the fallopian tubes, omentum, and peritoneum. The patient received anti-TB treatment after surgery. Six months after the operation, the patient had no abdominal pain and no major changes in menstruation. Our findings suggest that a timely operation is required for patients with an adnexal mass. During surgery, even if the lesion is similar to a malignant tumor, the surgical approach needs to be cautiously chosen for young patients without children. The patient's postoperative fertility must be taken into consideration.

Keywords: Ovarian serous cystadenoma; abdominal pain; fallopian tube; fertility; genital tuberculosis; miliary white nodule; peritoneum.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Cystadenofibroma*
  • Fallopian Tubes
  • Female
  • Humans
  • Ovarian Neoplasms* / complications
  • Ovarian Neoplasms* / diagnostic imaging
  • Ovarian Neoplasms* / surgery
  • Tuberculosis, Female Genital* / complications
  • Tuberculosis, Female Genital* / diagnosis
  • Ultrasonography